Post Menopausal

James Cima ESTRADIOL (E2), HORMONES

ESTROGENS

Estradiol (E2) is the most active estrogen and is used to evaluate menstrual and fertility conditions. In males, it is used to evaluate estrogen producing tumors. Estriol (E3) is the chief urine-monitoring hormone in pregnancy. 

WOMEN 60-400 60-400

POSTMENOPAUSAL <130 <130

ESTRADIOL URINE LEVELS ARE INCREASED IN: 

  1. Estrogen producing tumors 

  2. Hepatic cirrhosis 

  3. Hyperthyroidism 

  4. Precocious puberty 

  5. Feminization in children 

  6. During menstruation, before ovulation and between the 23rd to the 41st week of 
gestation 


 

ESTRADIOL URINE LEVELS ARE DECREASED IN: 

  1. Hypogonadism 

  2. Hypofunctioning hypothalamus 

  3. Hypofunctioning pituitary 

  4. Hypofunctioning adrenals 

  5. Menopause 


ESTRIOL URINE LEVELS ARE INCREASED IN: 

  1. Pregnancy


ESTRIOL URINE LEVELS ARE DECREASED IN: 

  1. Placental insufficiency 

  2. Congenital heart disease 

  3. Down’s syndrome 


BLOOD AND URINE TOTAL ESTROGENS LEVELS ARE ELEVATED IN: 

  1. Malignant neoplasms of the adrenals 

  2. Malignant neoplasms of the ovaries 

  3. Benign neoplasms of the ovaries 

  4. Lutein cell tumor of the ovaries 

  5. Theca cell tumor of the ovaries 

  6. Testicular tumors 


BLOOD AND URINE TOTAL ESTROGENS ARE DECREASED IN: 

  1. Hypopituitism 

  2. Hypofunctioning hypothalamus 

  3. Hypofunctioning ovaries 

  4. Intrauterine death 

  5. Menopause 

  6. Anorexia nervosa 

  7. Preeclampsia