Potassium

ELECTROLYTES

The blood electrolytes include sodium, potassium, chloride, and the bicarbonate (HCO3) ion.
Sodium, potassium, and chloride enter the body via ingestion of food.
Carbon dioxide, on the other hand, originates within the body via the metabolic process of carbohydrates, fats, and proteins.
Normally the excretion of sodium, potassium, and water is equal to their intake. The kidneys secrete 80-90 percent of all electrolytes.
Excessive carbon dioxide stimulates the respiratory centers in the brainstem to increase respiration. Therefore, the kidneys and the lungs control sodium, chloride, potassium, water, and carbon dioxide thus exerting control over the acid/alkaline balance in the body.
There are also many other organs, and glands involved in this process, such as the posterior pituitary, adrenals, bowel, and uterus/prostate.
The purpose of electrolytes is to set up a shifting mechanism in the cell membrane via oxidation, allowing increased or decreased permeability to that membrane site.
Sodium, which is found in high concentration outside the cell, has the ability to gather up substances (foods), and bring them to active membrane sites.
Chloride is found in the cell membrane and acts as a “doorman” allowing or disallowing exchanges between the intracellular and extracellular fluids.
Potassium, which is found in high concentrations within cells, oxidizes chloride, and allows sodium, with the food to cross the cell membrane and enter the cell.
Sodium, potassium, chloride, calcium, and hydrogen are all transported via active transport.
POTASSIUM

Potassium is intracellular, lining the inside of all cell membranes and affecting intracellular fluids, osmotic pressure, buffering viscosity (potassium bicarbonate is the primary intracellular inorganic buffer). When there is a decrease in potassium bicarbonate you have acid cells, which excites the respiratory centers so the patient hyperventilates. Metabolic acidosis or diabetic ketoacidosis drives potassium out of the cells, affecting electrolyte balance, water retention and carbon dioxide transport in red blood cells. Potassium is responsible via the posterior pituitary for oxidizing secondary hydrogen chloride (affecting adrenal function), allowing the sodium-aggregated substances to cross the cell membrane by affecting the membranes permeability.
Potassium is the only substance, which allows oxygen into unoxygenated tissue. About 90% of the body’s potassium supply is intracellular with only a small percent in the serum.
80% of that is found in the muscles (used for muscular contraction) and in the bones. Potassium levels are regulated by the Na/K ATPase pump which requires magnesium for proper function.
Potassium is necessary for proper function of mineralocorticoids, (aldosterone and deoxycorticosterone) thus maintaining sodium concentration and alkaline reserve.
Therefore, potassium is of great value to the posterior pituitary (ADH/oxytocin), the pineal, and the adrenal cortex via aldosterone secretion.
Potassium along with sodium regulate renal acid-base balance, by substituting hydrogen ions for sodium and potassium in the renal tubules.
Potassium also facilitates oxygen to the myocardium and oxidizes the S.A. node of the heart.
The heart has the highest potassium concentration in the body. Potassium along with calcium and magnesium controls the rate and force of contraction in heart muscle.
It is the primary oxidizer of the body capable of expressing all cellular needs.
Potassium also regulates neurological impulses via osmotic pressure gradients throughout the nervous system.
Potassium directs carbohydrate digestion by polarizing minerals associated with carbohydrate digestion, from the time the carbohydrate enters the body until the cell utilizes it.
Potassium also makes proteins soluble and regulates protein synthesis.
80-90 percent of potassium in the cells is excreted by the kidneys (resulting in the loss of 40-50 mEq/L per day even during fasting) with the remainder excreted by the stool and through sweating

POTASSIUM IS LOW WHEN
General considerations:

¬ Increase water intake
¬ Increase magnesium intake
¬ Decrease calcium intake
¬ Increase potassium intake
¬ Decrease carbohydrate intake

Globulin Total

GLOBULIN

Organs that are responsible for globulin production are the liver, thyroid, spleen and the rest the immune system.

There are four types of globulins alpha 1,2, beta and Gamma. There a few groups of gamma globulins with one group being the immunoglobulins (IgA, IgG. IgM), which produce our antibodies.
The thymus produces α and β globulins know as thymoglobulin using Vitamin T and copper for its production.
The thyroid produces thyroglobulins that form thyroxin and triiodothyronine via vitamin K and iodine.
The spleen produces spleenoglobulins that require vitamin E and iron for its production.

Globulin also acts as a polarized colloidal substance necessary for specific glandular hormonal function by acting as a transport mechanism for many hormones such as sex hormone binding globulin.
Globulin also assists in:
*Toxin neutralization by binding soluble antigens in the blood and intracellular spaces
*Red blood cell production
*Antibody formation
*Protection of the gastrointestinal mucosa
*And is also necessary via the intrinsic factor for digestion and absorption.

Globular proteins can be affected via:
*Nutrition- lack of protein
*Liver
*Thyroid
*Spleen
*Thymus